What is Alzheimer’s disease?
Alzheimer's disease is a physical condition caused by the build-up of proteins (amyloid plaques and tangles) in the brain. This protein build-up gradually blocks the connections between nerve cells, causing them to die, which leads to a decline in brain function. It primarily affects the hippocampus, the area of the brain responsible for memory.
According to the UK Dementia Research Institute, in the UK, almost 1 million people live with dementia, with Alzheimer's accounting for 60-80% of all cases.
What causes Alzheimer’s disease?
There is no single cause of Alzheimer’s. Instead, it develops due to a combination of genetic, lifestyle, and environmental factors, including:
- Age: The biggest risk factor – most cases are diagnosed after 65.
- Genetics: A family history of Alzheimer’s can slightly increase risk, particularly for early-onset forms linked to specific genes.
- Protein build-up: The defining plaques and tangles interfere with cell function and trigger inflammation.
- Health and lifestyle: Factors such as cardiovascular disease, diabetes, poor sleep, head injuries, and lack of exercise may contribute.
Although there is currently no cure, early diagnosis and the right support – such as specialist Alzheimer’s care at home – can help slow progression and maintain quality of life.